… (CRC) is the second most frequent deadly cancer in the United State. The proposed …
Etiologically, colon cancer is caused by spread of colorectal cancer cells to other parts of the body. …

… or PGs in colon carcinoma lines and overexpressed in colon … roles of those molecules in
colon cancer in the context of PG/… inhibitors, providing alternative approaches in colon cancer. …

… cyclooxygenase-2 inhibitors. A single placebo-controlled randomized trial of aspirin has shown
long-term colorectal cancer … chemopreventive effect of aspirin and other cyclooxygenase …

… PGI 2 is an alternative approach. In this direction, we have developed LFA9, with dual 5-LOX
and mPGES-1 inhibitor as a safer colon cancer chemopreventive that was observed to be …

… of the cyclooxygenase-2 (COX-2) in rectal cancer treated with … of preoperative treatment of
rectal cancer with regards to the … , and Scopus databases on 1 January 2021 with the usage …

… Low dose aspirin, however, was ranked the safest among chemoprevention … had an inferior
safety profile (SUCRA=0.51). Efficacy of agents for reducing metachronous colorectal cancer …

… all colon cancer types [44] and its inhibition, contemporary to the block of COX2, is an efficient
strategy to halt colon cancer … of cyclooxygenase2 inhibitor for potential chemopreventive …

… Cyclooxygenase 2 (COX-2) activity was determined by using rat ELISA Kit (My … as one
of the possible mechanisms of inhibition of cancer development, and many chemopreventive …

… Chemoprevention by celecoxib in mammary carcinoma was … (OS), whereas in colorectal
cancer, infiltration of TAMs in the … whether these markers of cancer-associated inflammation are …

… Targeting the molecules (COX-2 cyclooxygenase 2, NF-kB, VEGF) involved in the … a few
NSAIDs such as aspirin, sulindac, and celecoxib and colorectal cancer chemoprevention was …